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Treat Your Osteoarthritis with Alpha-2-Macroglobulin (A2M)

Many people suffer from osteoarthritis. As we age, the cartilage, and the bone underneath it, wears out causing joint stiffness and pain. After a period of time, severe joint treatment, such as reconstruction or replacement, becomes the only option.

Less invasive treatments, however, like Alpha-2-Macroglobulin, also known as A2M, can slow down the need for more invasive treatments.

What is A2M treatment and how does it help osteoarthritis?

A special molecule called Alpha-2-Macroglobulin is naturally found in your own blood. This molecule protects against cartilage breakdown. Healthy joints contain sufficient enough A2M to continually ward off invading enzymes.  But, when A2M production slows, a group of destructive enzymes, known as Matrix Metalloproteinases, or MMPs, begin to cause the inflammation related to osteoarthritis. During treatment, A2M targets MMPs, captures them and eliminates them through your body’s natural processes.

Treatment is pretty simple and straightforward. Blood is drawn during your visit. Then, through a patented process, the A2M in the blood sample is isolated and concentrated. The concentrated A2M is then injected into the injured joint.

Are You a Candidate for A2M therapy?

A simple test determines whether or not you are a good candidate for A2M treatment. This free diagnostic test looks for a unique biomarker in your joint or disc space called Fibronectin-Aggrecan Complex, or FAC. When the results of the test show a positive amount of FAC, it means the destructive enzymes, or MMPs, are present. In most cases, this makes you a candidate for A2M treatment.

Interested in learning more?

At Integrative Sports Medicine, we only offer treatments backed by research. A2M has proven effective during research. We’re happy to discuss whether or not it’s the right treatment for you.